For Drug Discovery Wiki: Advil Dual Action

On February 28 of this year, the FDA approved Advil Dual Action (ibuprofen and acetaminophen) as an over the counter (OTC) medication. There is a fixed dose combination of ibuprofen, which is an NSAID and the active ingredient in Advil. The other portion is acetaminophen, which is the active ingredient in Tylenol. It will be used for the relief of pain. The company that made this medication was GlaxoSmithKline Consumer Healthcare LP. It is the first FDA-approved OTC combination of acetaminophen and ibuprofen.

The submission for the drug has data from seven clinical trials with three focusing on efficacy and safety in pain relief. Data shows an indication with pain relief and the combination has higher efficacy than ibuprofen or acetaminophen alone. I found this specific drug to be very interesting because I am so used to seeing patients use either ibuprofen or acetaminophen due to their properties. I have heard cases of patients taking both, which have many beneficial effects. It is interesting to take note that not all patients would be taking this medication because of the NSAID portion, for example. How will attract consumers and will there be a large population taking this drug?

https://www.drugs.com/newdrugs/fda-approves-advil-dual-action-ibuprofen-acetaminophen-over-counter-pain-5174.html